Variability vs. Disability

Resources

Abondio, P., Sazzini, M., Garagnani, P., Boattini, A., Monti, D., Franceschi, C., ... & Giuliani, C. (2019). The genetic variability of APOE in different human populations and its implications for longevity. Genes, 10(3), 222. https://doi.org/10.3390/genes10030222

Adeyemo, A., & Rotimi, C. (2010). Genetic variants associated with complex human diseases show wide variation across multiple populations. Public Health Genomics, 13(2), 72-79. https://doi.org/10.1159/000218711

Anastasiou, D., & Kauffman, J. M. (2011). A social constructionist approach to disability: Implications for special education. Exceptional Children, 77(3), 367-384. https://doi.org/10.1177/001440291107700307

Beaty, R. E., Seli, P., & Schacter, D. L. (2019). Network neuroscience of creative cognition: mapping cognitive mechanisms and individual differences in the creative brain. Current Opinion in Behavioral Sciences, 27, 22-30. https://doi.org/10.1016/j.cobeha.2018.08.013

Bomba, L., Walter, K., & Soranzo, N. (2017). The impact of rare and low-frequency genetic variants in common disease. Genome Biology, 18(1), 77. https://doi.org/10.1186/s13059-017-1212-4

Borsboom, D., Cramer, A. O., & Kalis, A. (2019). Brain disorders? Not really: Why network structures block reductionism in psychopathology research. Behavioral and Brain Sciences, 42(e2), 1-63. https://doi.org/10.1017/S0140525X17002266

Brooke, J. L., & Larsen, C. S. (2014). The nurture of nature: genetics, epigenetics, and environment in human biohistory. The American Historical Review, 119(5), 1500-1513. https://doi.org/10.1093/ahr/119.5.1500

Brunet, A., et al. (2014). Trauma reactivation plus propranolol is associated with durably low physiological responding during subsequent script-driven traumatic imagery. Canadian Journal of Psychology, 59(4), 228-232. https://doi.org/10.1177/070674371405900408

CAST (2013). Addressing the variability of learners in Common Core-aligned assessments: Policies, practices, and universal design for learning. Policy Statement. Author.

Chapman, R. (2020). Neurodiversity, disability, wellbeing. Neurodiversity studies: A new critical paradigm.

Chikara, R. K., & Ko, L. W. (2020). Prediction of human inhibition brain function with inter-subject and intra-subject variability. Brain Sciences, 10(10), 726. https://doi.org/10.3390/brainsci10100726

circlvideos (2012, January 30). Todd Rose: Variability matters  [Video] (10:12) YouTube. https://www.youtube.com/watch?v=8WClnVjCEVM

Clouder, L., Karakus, M., Cinotti, A., Ferreyra, M. V., Fierros, G. A., & Rojo, P. (2020). Neurodiversity in higher education: a narrative synthesis. Higher Education, 1-22. https://doi.org/10.1007/s10734-020-00513-6

Cochran-Smith, M., & Dudley-Marling, C. (2012). Diversity in teacher education and special education: The issues that divide. Journal of Teacher Education, 63(4), 237-244. https://doi.org/10.1177/0022487112446512

Connor, D. J., & Bejoian, L. (2014). Cripping school curricula: 20 ways to re-teach disability. Review of Disability Studies: An International Journal, 3(3).

Corby, D., Taggart, L., & Cousins, W. (2015). People with intellectual disability and human science research: A systematic review of phenomenological studies using interviews for data collection. Research in Developmental Disabilities, 47, 451-465. https://doi.org/10.1016/j.ridd.2015.09.001

Darda, K. M., Butler, E. E., & Ramsey, R. (2020). Individual differences in social and non-social cognitive control. Cognition, 202, Article 104317. https://doi.org/10.1016/j.cognition.2020.104317

Deacon, T. W. (2017). Human variability and the origins and evolution of language. In On human nature (pp. 557-564). Academic Press. https://doi.org/10.1016/B978-0-12-420190-3.00032-6

Dodge, R. (1931). Conditions and consequences of human variability. Yale University Press.

Dolcos, F., Katsumi, Y., Moore, M., Berggren, N., de Gelder, B., Derakshan, N., ... & Pegna, A. J. (2020). Neural correlates of emotion-attention interactions: From perception, learning, and memory to social cognition, individual differences, and training interventions. Neuroscience and Biobehavioral Reviews, 108, 559-601. https://doi.org/10.1016/j.neubiorev.2019.08.017

Doyle, N. (2020). Neurodiversity at work: a biopsychosocial model and the impact on working adults. British Medical Bulletin, 135(1), 108. doi: 10.1093/bmb/ldaa021

Fisher, R. A. (1919). The causes of human variability. The Eugenics Review, 10(4), 213-220.

Forbes, K. (2019). The role of individual differences in the development and transfer of writing strategies between foreign and first language classrooms. Research Papers in Education, 34(4), 445-464. https://doi.org/10.1080/02671522.2018.1452963

Gladilin, Y. A., Fomkina, O. A., Muzurova, L. V., Anisimova, E. A., Aleshkina, O. Y., Khairullin, R. M., ... & Konnov, V. V. (2019). Variability of human cerebral hemispheres temporal operculum. Editorial Advisory Board, 26.

Goldstein, D. B. (2009). Common genetic variation and human traits. New England Journal of Medicine, 360(17), 1696.

Goodley, D., & Runswick-Cole, K. (2016). Becoming dishuman: Thinking about the human through dis/ability. Discourse: Studies in the Cultural Politics of Education, 37(1), 1-15. https://doi.org/10.1080/01596306.2014.930021

Guerra, A., López-Alonso, V., Cheeran, B., & Suppa, A. (2020). Variability in non-invasive brain stimulation studies: reasons and results. Neuroscience Letters, 719, 133330. https://doi.org/10.1016/j.neulet.2017.12.058

Haggarty, P. (2015). Genetic and metabolic determinants of human epigenetic variation. Current Opinion in Clinical Nutrition & Metabolic Care, 18(4), 334-338. https://doi.org/10.1097/mco.0000000000000194

Hulse, A. M., & Cai, J. J. (2013). Genetic variants contribute to gene expression variability in humans. Genetics, 193(1), 95-108. https://doi.org/10.1534/genetics.112.146779

Iacob, C. I., Avram, E., Cojocaru, D., & Podina, I. R. (2020). Resilience in familial caregivers of children with developmental disabilities: A meta-analysis. Journal of Autism and Developmental Disorders, 1-16. https://doi.org/10.1007/s10803-020-04473-9

Iuculano, T., Padmanabhan, A., Chen, L., Nicholas, J., Mitsven, S., de los Angeles, C., & Menon, V. (2020). Neural correlates of cognitive variability in childhood autism and relation to heterogeneity in decision-making dynamics. Developmental Cognitive Neuroscience, 42, Article 100754. https://doi.org/10.1016/j.dcn.2020.100754

Kantonen, T., Karjalainen, T., Isojärvi, J., Nuutila, P., Tuisku, J., Rinne, J., ... & Nummenmaa, L. (2020). Interindividual variability and lateralization of μ-opioid receptors in the human brain. Neuroimage, 215, August 2020, 116922. https://doi.org/10.1016/j.neuroimage.2020.116922

Karalunas, S. L., Hawkey, E., Gustafsson, H., Miller, M., Langhorst, M., Cordova, M., ... & Nigg, J. T. (2018). Overlapping and distinct cognitive impairments in Attention-Deficit/Hyperactivity and Autism Spectrum Disorder without Intellectual Disability. Journal of Abnormal Child Psychology, 46(8) 1-12. https://dx.doi.org/10.1007%2Fs10802-017-0394-2

Keinan, A., & Clark, A. G. (2012). Recent explosive human population growth has resulted in an excess of rare genetic variants. Science, 336(6082), 740-743. DOI: 10.1126/science.1217283

Kidd, E., & Donnelly, S. (2020). Individual differences in first language acquisition. Annual Review of Linguistics, 6, 319-340. https://doi.org/10.1146/annurev-linguistics-011619-030326

Kistler, D. S. (2015). A business case for disability human rights? Assessing affirmative action measures as a tool for enhancing the right to work and employment of persons with disabilities. Master's thesis. University of Oslo, Faculty of Law.

Koh, C. (2020). A qualitative meta-analysis on the use of serious games to support learners with intellectual and developmental disabilities: What we know, what we need to know and what we can do. International Journal of Disability, Development and Education, 1-32. https://doi.org/10.1080/1034912X.2020.1746245

Kircher, M., Witten, D. M., Jain, P., O'Roak, B. J., Cooper, G. M., & Shendure, J. (2014). A general framework for estimating the relative pathogenicity of human genetic variants. Nature Genetics, 46(3), 310-315. https://doi.org/10.1038/ng.2892

Knight, J. C. (2014). Approaches for establishing the function of regulatory genetic variants involved in disease. Genome Medicine, 6(10), 1-15. https://doi.org/10.1186/s13073-014-0092-4

Lévesque, M. L., Casey, K. F., Szyf, M., Ismaylova, E., Ly, V., Verner, M. P., ... & Boivin, M. (2014). Genome-wide DNA methylation variability in adolescent monozygotic twins followed since birth. Epigenetics, 9(10), 1410-1422. https://doi.org/10.4161/15592294.2014.970060

Lightfoot, E., & DeZelar, S. (2020). Parent centered planning: A new model for working with parents with intellectual and developmental disabilities. Children and Youth Services Review, 105047. https://doi.org/10.1016/j.childyouth.2020.105047

Lopresti, A. L. (2020). Association between micronutrients and heart rate variability: A review of human studies. Advances in Nutrition, 11(3), 559-575. https://doi.org/10.1093/advances/nmz136

Lory, C., Mason, R. A., Davis, J. L., Wang, D., Kim, S. Y., Gregori, E., & David, M. (2020). A meta-analysis of challenging behavior interventions for students with developmental disabilities in inclusive school settings. Journal of Autism and Developmental Disorders, 1-17. https://doi.org/10.1007/s10803-019-04329-x

Marderstein, A. R., Davenport, E. R., Kulm, S., Van Hout, C. V., Elemento, O., & Clark, A. G. (2020). Leveraging phenotypic variability to identify genetic interactions in human phenotypes. The American Journal of Human Genetics, 108(1), 49-67. https://doi.org/10.1016/j.ajhg.2020.11.016

Masefield, S. C., Prady, S. L., Sheldon, T. A., Small, N., Jarvis, S., & Pickett, K. E. (2020). The caregiver health effects of caring for young children with developmental disabilities: A meta-analysis. Maternal and Child Health Journal, 1-14. https://doi.org/10.1007/s10995-020-02896-5

McDermott, K. B., & Zerr, C. L. (2019). Individual differences in learning efficiency. Current Directions in Psychological Science, 28(6), 607-613. https://doi.org/10.1177/0963721419869005

Mitra, S. (2018). The human development model of disability, health and wellbeing. In Disability, health and human development (pp. 9-32). Palgrave Pivot. https://doi.org/10.1057/978-1-137-53638-9_2

Morioka, H., Ijichi, S., Ijichi, N., Ijichi, Y., & King, B. H. (2019). Developmental social vulnerability as the intrinsic origin of psychopathology: A paradigm shift from disease entities to psychiatric derivatives within human diversity. Medical Hypotheses, 126, 95-108. https://doi.org/10.1016/j.mehy.2019.03.015

Musso, M. F., Boekaerts, M., Segers, M., & Cascallar, E. C. (2019). Individual differences in basic cognitive processes and self-regulated learning: their interaction effects on math performance. Learning and Individual Differences, 71, 58-70. https://doi.org/10.1016/j.lindif.2019.03.003

National Center for Learning Disabilities. (2016). Reports and studies. https://www.ncld.org/research

National Center on Universal Design for Learning at CAST. (2013). Research library. https://www.castsoftware.com/resources/research-library

National College for Teaching & Leadership. (2015, August 7). Advanced training materials for autism; dyslexia; speech, language and communication; emotional, social and behavioural difficulties; moderate learning difficulties. https://www.sendgateway.org.uk/resources.advanced-training-materials-for-autism-dyslexia-speech-language-and-communication-emotional-social-and-behavioural-difficulties-moderate-learning-difficulties_1.html

The National Library of Medicine, The. (2016). NCBI Human variation and medical genetics resources. [Video] (1:02:55). YouTube. https://www.youtube.com/watch?v=zdIg7zGNkbg&ab_channel=TheNationalLibraryofMedicine

Niermann, H. C., Figner, B., & Roelofs, K. (2017). Individual differences in defensive stress-responses: the potential relevance for psychopathology. Current Opinion in Behavioral Sciences, 14, 94-101. https://doi.org/10.1016/j.cobeha.2017.01.002

Orrù, V., Steri, M., Sole, G., Sidore, C., Virdis, F., Dei, M., ... & Cucca, F. (2013). Genetic variants regulating immune cell levels in health and disease. Cell, 155(1), 242-256. https://doi.org/10.1016/j.cell.2013.08.041

Ortmann, D., & Vallier, L. (2017). Variability of human pluripotent stem cell lines. Current Opinion in Genetics & Development, 46, 179-185. https://doi.org/10.1016/j.gde.2017.07.004

Pellicano, E., & den Houting, J. (2022). Annual Research Review: Shifting from ‘normal science’to neurodiversity in autism science. Journal of Child Psychology and Psychiatry, 63(4), 381-396. https://doi.org/10.1111/jcpp.13534

Pickrell, J. K., Berisa, T., Liu, J. Z., Ségurel, L., Tung, J. Y., & Hinds, D. A. (2016). Detection and interpretation of shared genetic influences on 42 human traits. Nature Genetics, 48(7), 709. https://doi.org/10.1038/ng.3570

Plomin, R., Kovas, Y, and Haworth, C.M.A. (2007). Generalist genes: Genetic links between mind, brain, and education. Mind Brain Education, 1(1), 11-19. https://dx.doi.org/10.1111%2Fj.1751-228X.2007.00002.x

Posner, M. (2003). Neural systems and individual differences: A commentary on Frames of Mind: the theory of multiple intelligences Paper presented at the annual meeting of the American Educational Research Association, Chicago.

Power, R. A., & Pluess, M. (2015). Heritability estimates of the Big Five personality traits based on common genetic variants. Translational Psychiatry, 5(7), e604-e604. DOI https://doi.org/10.1038/tp.2015.96

Ramus, F. (2006). Genes, brain, and cognition: a roadmap for the cognitive scientist. Cognition, 101, 247-269. https://doi.org/10.1016/j.cognition.2006.04.003

Richetto, J., & Meyer, U. (2020). Epigenetic modifications in Schizophrenia and related disorders: Molecular scars of environmental exposures and source of phenotypic variability. Biological Psychiatry, 89(3), 215-226 https://doi.org/10.1016/j.biopsych.2020.03.008

Rao, M. (2016). Brain development: Neuro-behavioral perspectives in developmental disabilities. The Clinical Bulletin of the Developmental Disabilities Division, 24(1).

Robison, M. A., Mann, T. B., & Ingvarsson, E. T. (2020). Life skills instruction for children with developmental disabilities. Journal of Applied Behavior Analysis, 53(1), 431-448.  https://doi.org/10.1002/jaba.602

Rogers, C., & Tuckwell, S. (2016). Co-constructed caring research and intellectual disability: An exploration of friendship and intimacy in being human. Sexualities, 19(5-6), 623-640. https://doi.org/10.1177/1363460715620572

Rose, T. (2013). The myth of average [Video]. (18:26 minutes). TED Ed. https://ed.ted.com/on/4s8O5loM#watch

Ross, R., Goodpaster, B. H., Koch, L. G., Sarzynski, M. A., Kohrt, W. M., Johannsen, N. M., ... & Bouchard, C. (2019). Precision exercise medicine: understanding exercise response variability. British Journal of Sports Medicine, 53(18), 1141-1153. http://dx.doi.org/10.1136/bjsports-2018-100328

Rotwein, P. (2020). Revisiting the population genetics of human height. Journal of the Endocrine Society, 4(4), bvaa025. https://doi.org/10.1210/jendso/bvaa025

Russell, G. (2020). Critiques of the neurodiversity movement. Autistic Community and the Neurodiversity Movement, 287. https://doi.org/10.1007/978-981-13-8437-0

Sadnicka, A., & Hamada, M. (2020). Plasticity and dystonia: a hypothesis shrouded in variability. Experimental Brain Research, 1-7. https://doi.org/10.1007/s00221-020-05773-3

Sarafian, D., Miles-Chan, J. L., Yepuri, G., Montani, J. P., Schutz, Y., & Dulloo, A. G. (2013). A standardized approach to study human variability in isometric thermogenesis during low-intensity physical activity. Frontiers in Physiology, 4, Article 155. https://dx.doi.org/10.3389%2Ffphys.2013.00155

Sasani, T. A., Pedersen, B. S., Gao, Z., Baird, L., Przeworski, M., Jorde, L. B., & Quinlan, A. R. (2019). Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation. eLife, 8, e46922.

Schneps, M. (2015, January). Dyslexia can deliver benefits. Scientific American Mind. https://www.scientificamerican.com/article/dyslexia-can-deliver-benefits/

Shields, K., & Beversdorf, D. (2020). A dilemma for neurodiversity. Neuroethics, 2020. https://doi.org/10.1007/s12152-020-09431-x

Shogren, K.A., et al. (2010). Locus of control orientations in students with intellectual disability, learning disabilities, and no disabilities: A latent growth curve analysis. Research Practice for Persons with Severe Disabilities, 35(3-4), 80-92. https://doi.org/10.2511/rpsd.35.3-4.80

Snow, C. (2008). Varied developmental trajectories: Lessons for educators. Mind, Brain, and Education, 2(2), 59-61. https://doi.org/10.1111/j.1751-228X.2008.00032.x

Sonuga-Barke, E., & Thapar, A. (2021). The neurodiversity concept: is it helpful for clinicians and scientists? The Lancet Psychiatry, 8(7), 559-561. https://doi.org/10.1016/S2215-0366(21)00167-X

Spielman, R. S., Bastone, L. A., Burdick, J. T., Morley, M., Ewens, W. J., & Cheung, V. G. (2007). Common genetic variants account for differences in gene expression among ethnic groups. Nature Genetics, 39(2), 226-231. https://doi.org/10.1038/ng1955

Sun, H., & Liu, Y. (2019). The causes of human variability: a Darwinian view. International Journal of Epidemiology, 48(1), 319-320. .https://doi.org/10.1093/ije/dyx261

Telenti, A., & di Iulio, J. (2020). Regulatory genome variants in human susceptibility to infection. Human Genetics, 139(6), 759-768. https://doi.org/10.1007/s00439-019-02091-9

Thomas, M. S., Alfageme, O. O., D’Souza, H., Patkee, P. A., Rutherford, M. A., Mok, K. Y., ... & LonDownS Consortium. (2020). A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment. Research in Developmental Disabilities, 104, Article 103638. https://doi.org/10.1016/j.ridd.2020.103638

Timpson, N. J., Greenwood, C. M., Soranzo, N., Lawson, D. J., & Richards, J. B. (2018). Genetic architecture: the shape of the genetic contribution to human traits and disease. Nature Reviews Genetics, 19(2), 110. https://doi.org/10.1038/nrg.2017.101

Uddin, L. Q., Supekar, K., & Menon, V. (2010). Typical and atypical development of functional human brain networks: insights from resting-state FMRI. Frontiers in Systems Neuroscience, 4, Article 21. https://doi.org/10.3389/fnsys.2010.00021

United Kingdom Department of Education. (2012). Training materials for teachers of learners with severe, profound, and complex learning difficulties. http://www.complexneeds.org.uk/

Van Der Made, C. I., Simons, A., Schuurs-Hoeijmakers, J., Van Den Heuvel, G., Mantere, T., Kersten, S., ... & Hoischen, A. (2020). Presence of genetic variants among young men with severe COVID-19. Jama, 324(7), 663-673. doi:10.1001/jama.2020.13719

Voon, V., Derbyshire, K., Rück, C., Irvine, M. A., Worbe, Y., Enander, J., ... & Bullmore, E. T. (2015). Disorders of compulsivity: a common bias towards learning habits. Molecular Psychiatry, 20(3), 345-352. https://doi.org/10.1038/mp.2014.44

Walker, N., Monaghan, P., Schoetensack, C., & Rebuschat, P. (2020). Distinctions in the acquisition of vocabulary and grammar: An individual differences approach. Language Learning, 70(52), 221-254. https://doi.org/10.1111/lang.12395

Wuensch, L., Pool, E. R., & Sander, D. (2021). Individual differences in learning positive affective value. Current Opinion in Behavioral Sciences, 39, 19-26. https://doi.org/10.1016/j.cobeha.2020.11.001

Wolfers, T., Beckmann, C. F., Hoogman, M., Buitelaar, J. K., Franke, B., & Marquand, A. F. (2020). Individual differences v. the average patient: mapping the heterogeneity in ADHD using normative models. Psychological Medicine, 50(2), 314-323. https://dx.doi.org/10.1017%2FS0033291719000084

Yashin, A. I., Wu, D., Arbeev, K. G., & Ukraintseva, S. V. (2010). Joint influence of small-effect genetic variants on human longevity. Aging, 2(9), 612.  doi: 10.18632/aging.100191

Zhang, G., Muglia, L. J., Chakraborty, R., Akey, J. M., & Williams, S. M. (2013). Signatures of natural selection on genetic variants affecting complex human traits. Applied & Translational Genomics, 2, 78-94. https://doi.org/10.1016/j.atg.2013.10.002

Other Resources

Annenberg  Learner. (2010). Reading with half a brain. https://www.learner.org/series/neuroscience-in-the-classroom/different-learners-different-minds/reading-with-half-a-brain/

Annenberg  Learner. (2012). Unit 1: Different brains. https://www.learner.org/series/neuroscience-in-the-classroom/different-brains/

Annenberg  Learner. (2012). Unit 4: Different learners, different minds https://www.learner.org/series/neuroscience-in-the-classroom/different-learners-different-minds/

Annenberg  Learner. (2012). Unit 6: Implications for schools https://www.learner.org/series/neuroscience-in-the-classroom/implications-for-schools/

Bartholomew Consolidated School Corporation video (2012, December 28). UDL in 5 minutes [Video] (5:28). YouTube. https://www.youtube.com/watch?v=2LigmnGaryQ

Bluefish TV.com (2007, December 11). Famous failures [Video] (1:16). YouTube. https://www.youtube.com/watch?v=Y6hz_s2XIAU

Colorado State University (n.d.). UDL Quick Tips. http://accessproject.colostate.edu/udl/documents/udl_quick_tips.pdf.

DNA Learning Center. (2020). Studying human variation. (49:15 minutes). Author. https://www.youtube.com/watch?v=5NdxQUpScrY&ab_channel=DNALearningCenter

Harvesct (2006, February 3). Patrick Henry Hughes [Video] (6:32). YouTube. https://www.youtube.com/watch?v=9xwCG0Ey2Mg&feature=youtu.be

Khan, S. (2015, November). Let’s teach for mastery, not for test scores! [Video] (10:50 minutes). TED Conferences https://www.ted.com/talks/sal_khan_let_s_teach_for_mastery_not_test_scores?utm_campaign=tedspread&utm_medium=referral&utm_source=tedcomshare

LaTour, F. (2013, March 31). Dropout at Harvard: What Todd Rose's unusual story says about why--and how--we should remake education. The Boston Globe. https://www3.bostonglobe.com/ideas/2013/03/30/dropout-harvard/3JEYV7sdiHzhlFNOapHSuO/story.html?arc404=true

Levine, M. (2011, July 17). Mel Levine: One mind at a time [Audio podcast episode]. In Morning edition. National Public Radio. https://www.npr.org/templates/story/story.php?storyId=4460341

Little Giant Steps (2011, May 6). Learning disabilities - not a life sentence [Video] (11:37). YouTube. https://www.youtube.com/watch?v=UZqOW7oJ8xo

Pazzanese, C. (2014, Nov. 11). Undermining Intelligence: Negative stereotypes can lead to cognitive drain among students identifying with the groups affected. Harvard Gazette. https://news.harvard.edu/gazette/story/2014/11/undermining-intelligence/?utm_source=SilverpopMailing&utm_medium=email&utm_campaign=11.10.2014%20%281%29

VIBRATIONZERO. (2012, May 5). The boy with the incredible brain [Video] (2:52). YouTube. https://www.youtube.com/watch?v=w-TJxI-WUMs&feature=youtu.be

Date of last update: 15-Dec-2022 CB

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