Default Mode Network

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Aguilar, D. D., & McNally, J. M. (2022). Subcortical control of the default mode network: Role of the basal forebrain and implications for neuropsychiatric disorders. Brain Research Bulletin, 185, 129–139. doi.org/10.1016/j.brainresbull.2022.05.005

Alam, T. R. G., Krieger-Redwood, K., Varga, D., Gao, Z., Horner, A. J., Hartley, T., ... & Jefferies, E. (2025). A double dissociation between semantic and spatial cognition in visual to default network pathways. eLife, 13, RP94902. https://doi.org/10.7554/eLife.94902.3

Bai, Y., Qu, J., Li, D., & Yin, H. (2024). Neural basis underlying the relation between internet addiction tendency and sleep quality: The intrinsic default-mode network connectivity pathways. International Journal of Psychophysiology, 195, 112264. https://doi.org/10.1016/j.ijpsycho.2023.112264

Bartoli, E., Devara, E., Dang, H. Q., Rabinovich, R., Mathura, R. K., Anand, A., ... & Shofty, B. (2024). Default mode network electrophysiological dynamics and causal role in creative thinking. Brain, awae199. https://doi.org/10.1093/brain/awae199

Blondé, P., Sperduti, M., Makowski, D., & Piolino, P. (2022). Bored, distracted, and forgetful: The impact of mind wandering and boredom on memory encoding. Quarterly Journal of Experimental Psychology, 75(1), 53-69. doi.org/10.1177/17470218211026301

Bontemps, A. P., Batky, B. D., Houser, R. A., & Salekin, R. T. (2022). Psychopathic traits, conduct problems, and the examination of self-referential processing using EEG in incarcerated adolescents. Journal of Psychopathology and Behavioral Assessment, 1-17. doi.org/10.1007/s10862-021-09945-5

Chan, A., Harvey, P., Hernandez-Cardenache, R., Alperin, N., Lee, S., Hunt, C., ... & Williams, K. (2024). Trauma and the default mode network: review and exploratory study. Frontiers in Behavioral Neuroscience, 18, 1499408. https://doi.org/10.3389/fnbeh.2024.1499408

Chen, Y. Y., Uljarevic, M., Neal, J., Greening, S., Yim, H., & Lee, T. H. (2022). Excessive functional coupling with less variability between salience and default mode networks in autism spectrum disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 7(9), 876-884.doi.org/10.1016/j.bpsc.2021.11.016

Chen, X., & Yan, C. G. (2021). Hypostability in the default mode network and hyperstability in the frontoparietal control network of dynamic functional architecture during rumination. NeuroImage, 241, Article 118427. doi.org/10.1016/j.neuroimage.2021.118427

Chou, T., Deckersbach, T., Dougherty, D. D., & Hooley, J. M. (2023). The default mode network and rumination in individuals at risk for depression. Social cognitive and affective neuroscience, 18(1), nsad032. https://doi.org/10.1093/scan/nsad032

Dai, Z., Shao, J., Zhou, H., Chen, Z., Zhang, S., Wang, H., ... & Lu, Q. (2022). Disrupted fronto-parietal network and default-mode network gamma interactions distinguishing suicidal ideation and suicide attempt in depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 113, Article 110475doi.org/10.1016/j.pnpbp.2021.110475

De Ridder, D. (2025). IS076 Mapping functional connectome of the default mode network for targeted neuromodulation. Neuromodulation, 28(1), S40. DOI: 10.1016/j.neurom.2024.09.085

Diede, N. T., Gyurkovics, M., Nicosia, J., Diede, A., & Bugg, J. M. (2022). The effect of context on mind-wandering in younger and older adults. Consciousness and Cognition, 97, Article 103256. doi.org/10.1016/j.concog.2021.103256

Dixon, M. L., Moodie, C. A., Goldin, P. R., Farb, N., Heimberg, R. G., Zhang, J., & Gross, J. J. (2022). Frontoparietal and default mode network contributions to self-referential processing in social anxiety disorder. Cognitive, Affective, & Behavioral Neuroscience, 22(1), 187-198. doi.org/10.3758/s13415-021-00933-6

Eryurek, K., Ulasoglu-Yildiz, C., Matur, Z., Öge, A. E., Gürvit, H., & Demiralp, T. (2022). Default mode and dorsal attention network involvement in visually guided motor sequence learning. Cortex, 146, 89-105. doi.org/10.1016/j.cortex.2021.10.006

Esposito, R., Bortoletto, M., Zacà, D., Avesani, P., & Miniussi, C. (2022). An integrated TMS-EEG and MRI approach to explore the interregional connectivity of the default mode network. Brain Structure and Function, 227(3), 1133-1144. doi.org/10.1007/s00429-022-02453-6

Fan, F., Liao, X., Lei, T., Zhao, T., Xia, M., Men, W., Wang, Y., Hu, M., Liu, J., Qin, S., Tan, S., Gao, J., Dong, Q., Tao, S., & He, Y. (2021). Development of the default-mode network during childhood and adolescence: A longitudinal resting-state fMRI study. NeuroImage, 226, Article 117581. doi.org/10.1016/j.neuroimage.2020.117581

Fukushima, T., & Yamaguchi, T. (2025). Effect of olfactory presentation timing on memory retention: Relationship to default mode network activity. In International conference on human-computer interaction (pp. 312-324). Springer, Cham. https://doi.org/10.1007/978-3-031-76803-3_18

Ganesan, S., Beyer, E., Moffat, B., Van Dam, N. T., Lorenzetti, V., & Zalesky, A. (2022). Focused attention meditation in healthy adults: A systematic review and meta-analysis of cross-sectional functional MRI studies. Neuroscience & Biobehavioral Reviews, 104846. doi.org/10.1016/j.neubiorev.2022.104846

Gbyl, K., Labanauskas, V., Lundsgaard, C. C., Mathiassen, A., Ryszczuk, A., Siebner, H. R., ... & Videbech, P. (2024). Electroconvulsive therapy disrupts functional connectivity between hippocampus and posterior default mode network. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 132, 110981. https://doi.org/10.1016/j.pnpbp.2024.110981

Goelman, G., Dan, R., Bezdicek, O., Jech, R., & Ekstein, D. (2024). Directed functional connectivity of the default-mode-network of young and older healthy subjects. Scientific Reports, 14(1), 4304. https://doi.org/10.1038/s41598-024-54802-6

Groot, J. M., Boayue, N. M., Csifcsák, G., Boekel, W., Huster, R., Forstmann, B. U., & Mittner, M. (2021). Probing the neural signature of mind wandering with simultaneous fMRI-EEG and pupillometry. NeuroImage, 224, Article 117412. doi.org/10.1016/j.neuroimage.2020.117412

Guo, Q., Zhu, R., Zhou, H., Ma, Z., He, Y., Wang, D., & Zhang, X. (2025). Reduced resting-state functional connectivity of default mode network subsystems in patients with obsessive-compulsive disorder. Journal of Affective Disorders, 369, 1108-1114. https://doi.org/10.1016/j.jad.2024.10.109

Haipt, A., Rosenbaum, D., Fuhr, K., Batra, A., & Ehlis, A. C. (2024). Differential effects of hypnotherapy and cognitive behavioral therapy on the default mode network of depressed patients. Frontiers in Psychology, 15, 1401946. https://doi.org/10.3389/fpsyg.2024.1401946

He, H., Li, Y., Chen, Q., Wei, D., Shi, L., Wu, X., & Qiu, J. (2021). Tracking resting-state functional connectivity changes and mind wandering: A longitudinal neuroimaging study. Neuropsychologia, 150, Article 107674. doi.org/10.1016/j.neuropsychologia.2020.107674

He, H., Hu, L., Zhang, X., & Qiu, J. (2021). Pleasantness of mind wandering is positively associated with focus back effort in daily life: Evidence from resting state fMRI. Brain and Cognition, 150, Article 105731. doi.org/10.1016/j.bandc.2021.105731

Ikemoto, S., von Ellenrieder, N., & Gotman, J. (2025). Interictal epileptiform discharge-related BOLD responses in the default mode network and subcortical regions. Clinical Neurophysiology, 170, 29-40. https://doi.org/10.1016/j.clinph.2024.11.017

Jubera-Garcia, E., Gevers, W., & Van Opstal, F. (2021). Local build-up of sleep pressure could trigger mind wandering: Evidence from sleep, circadian and mind wandering research. Biochemical Pharmacology, Article 114478. doi.org/10.1016/j.bcp.2021.114478

Lee, Y., Chahal, R., & Gotlib, I. H. (2024). The default mode network is associated with changes in internalizing and externalizing problems differently in adolescent boys and girls. Development and Psychopathology, 36(2), 834-843.  doi:10.1017/S0954579423000111

Li, Q., Xiang, G., Song, S., & Chen, H. (2022). How people reach their goals: Neural basis responsible for trait self-control association with hope. Personality and Individual Differences, 184, Article 111228. doi.org/10.1016/j.paid.2021.111228

Li, Y., Yu, X., Ma, Y., Su, J., Li, Y., Zhu, S., ... & Wang, J. (2023). Neural signatures of default mode network in major depression disorder after electroconvulsive therapy. Cerebral cortex, 33(7), 3840-3852. https://doi.org/10.1093/cercor/bhac311

Likitlersuang, J., Brown, E. M., Salat, D. H., Iverson, K. M., Werner, K., McGlinchey, R. E., Galovski, T. E., & Fortier, C. B. (2022). Neural correlates of traumatic brain injury in women survivors of intimate partner violence: A structural and functional connectivity neuroimaging study. Journal of Head Trauma Rehabilitation, 37(1), E30-E38.doi.org/10.1097/HTR.0000000000000758

Lloyd-Cox, J., Chen, Q., & Beaty, R. E. (2022). The time course of creativity: Multivariate classification of default and executive network contributions to creative cognition over time. Cortex, 156, 90-105. doi.org/10.1016/j.cortex.2022.08.008

Loukas, S., Lordier, L., Meskaldji, D. E., Filippa, M., Sa de Almeida, J., Van De Ville, D., & Hüppi, P. S. (2022). Musical memories in newborns: A resting state functional connectivity study. Human Brain Mapping, 43, 647–664. doi.org/10.1002/hbm.25677

Malagurski, B., Deschwanden, P. F., Jäncke, L., & Mérillat, S. (2022). Longitudinal functional connectivity patterns of the default mode network in healthy older adults. NeuroImage, 259, 119414.doi.org/10.1016/j.neuroimage.2022.119414

Mancuso, L., Cavuoti-Cabanillas, S., Liloia, D., Manuello, J., Buzi, G., Cauda, F., & Costa, T. (2022). Tasks activating the default mode network map multiple functional systems. Brain Structure and Function, 227(5), 1711-1734. doi.org/10.1007/s00429-022-02467-0

Meng, Y., Goubran, M., Rabin, J. S., McSweeney, M., Ottoy, J., Pople, C. B., ... & Lipsman, N. (2023). Blood–brain barrier opening of the default mode network in Alzheimer’s disease with magnetic resonance-guided focused ultrasound. Brain, 146(3), 865-872. https://doi.org/10.1093/brain/awad082

Menon, V. (2023). 20 years of the default mode network: A review and synthesis. Neuron, 111(16), 2469-2487. https://doi.org/10.1016/j.neuron.2023.04.023

Nogueira, M., Magalhães, J. D. S., Sampaio, A., Sousa, S., & Coutinho, J. F. (2025). Examining insula–default mode network functional connectivity and its relationship with heart rate variability. Brain Sciences, 15(1), 37. https://doi.org/10.3390/brainsci15010037

Norman, Y., Raccah, O., Liu, S., Parvizi, J., & Malach, R. (2021). Hippocampal ripples and their coordinated dialogue with the default mode network during recent and remote recollection. Neuron, 109(17), 2767-2780. https://doi.org/10.1016/j.neuron.2021.06.020

Oldham, S., Ball, G., & Fornito, A. (2022). Early and late development of hub connectivity in the human brain. Current Opinion in Psychology, 44, 321-329. oi.org/10.1016/j.copsyc.2021.10.010

Paiva, T., & Canas‐Simião, H. (2022). Sleep and violence perpetration: A review of biological and environmental substrates. Journal of Sleep Research, Article e13547. doi.org/10.1111/jsr.13547

Park, B., Lee, S., Jang, Y., & Park, H. Y. (2024). Affective dysfunction mediates the link between neuroimmune markers and the default mode network functional connectivity, and the somatic symptoms in somatic symptom disorder. Brain, Behavior, and Immunity, 118, 90-100. https://doi.org/10.1016/j.bbi.2024.02.017

Philippi, C. L., Bruss, J., Boes, A. D., Albazron, F. M., Deifelt Streese, C., Ciaramelli, E., Rudrauf, D., & Tranel, D. (2021). Lesion network mapping demonstrates that mind‐wandering is associated with the default mode network. Journal of Neuroscience Research, 99(1), 361-373. doi.org/10.1002/jnr.24648

Reddy, D. D., Davenport, E. M., Yu, F. F., Wagner, B., Urban, J. E., Whitlow, C. T., ... & Maldjian, J. A. (2021). Alterations in the magnetoencephalography default mode effective connectivity following concussion. American Journal of Neuroradiology, 42(10), 1776-1782. doi.org/10.3174/ajnr.A7232

Rahrig, H., Vago, D. R., Passarelli, M., Auten, A., Lynn, N. A., & Brown, K. W. (2022). Disrupting the resting state: Meta-analytic evidence that mindfulness training alters default mode network connectivity. Virginia Commonwealth University. doi.org/10.21203/rs.3.rs-1189676/v1

Ramanathan, D., Nan, J., Grennan, G., Jaiswal, S., Purpura, S., Manchanda, J., ... & Mishra, J. (2024). Modulation of posterior default mode network activity during interoceptive attention and relation to mindfulness. Biological Psychiatry Global Open Science, 4(6), 100384. https://doi.org/10.1016/j.bpsgos.2024.100384

Ronde, M., van der Zee, E. A., & Kas, M. J. (2024). Default mode network dynamics: An integrated neurocircuitry perspective on social dysfunction in human brain disorders. Neuroscience & Biobehavioral Reviews, 105839. https://doi.org/10.1016/j.neubiorev.2024.105839

Riegner, G., Posey, G., Oliva, V., Jung, Y., Mobley, W., & Zeidan, F. (2022). Disentangling self from pain: mindfulness meditation-induced pain relief is driven by thalamic-default mode network decoupling. Pain, 10-1097. doi: 10.1097/j.pain.0000000000002731

Sambuco, N. (2024). Cognition, emotion, and the default mode network. Brain and Cognition, 182, 106229. https://doi.org/10.1016/j.bandc.2024.106229

Sambuco, N., Bradley, M. M., & Lang, P. J. (2022). Narrative imagery: Emotional modulation in the default mode network. Neuropsychologia, 164, Article 108087. doi.org/10.1016/j.neuropsychologia.2021.108087

Sarna, K. K., Khan, A., Khan, W., & Saini, S. (2022). Neurocognitive underpinning of neurological disorders: Role of default mode network. In M. Rahman, W. H Almalki, M. Alrobaian, S. Beg, K.S. Alharbi, (eds) Hormone related cancer mechanistic and nanomedicines (pp. 269-297). Springer, Singapore. doi.org/10.1007/978-981-19-5558-7_13

Scarapicchia, V., Kwan, H., Czippel, A., & Gawryluk, J. R. (2024). Differences between resting-state fMRI BOLD variability and default mode network connectivity in healthy older and younger adults. Brain Connectivity, 14(7), 391-398. https://doi.org/10.1089/brain.2023.007

Seinfeld, S., Zhan, M., Poyo-Solanas, M., Barsuola, G., Vaessen, M., Slater, M., Sanchez-Vives, M. V., & de Gelder, B. (2021). Being the victim of virtual abuse changes default mode network responses to emotional expressions. Cortex, 135, 268-284. doi.org/10.1016/j.cortex.2020.11.018

Shao, X., Krieger-Redwood, K., Zhang, M., Hoffman, P., Lanzoni, L., Leech, R., ... & Jefferies, E. (2024). Distinctive and complementary roles of default mode network subsystems in semantic cognition. Journal of Neuroscience, 44(20). https://doi.org/10.1523/JNEUROSCI.1907-23.2024

Shen, Z., Yang, X., She, T., Zhao, G., Dou, Z., Luo, Y., ... & Yu, S. (2024). Deficits in brain default mode network connectivity mediate the relationship between poor sleep quality and anxiety severity. Sleep, 47(3), zsad296. https://doi.org/10.1093/sleep/zsad296

Smallwood, J., Bernhardt, B. C., Leech, R., Bzdok, D., Jefferies, E., & Margulies, D. S. (2021). The default mode network in cognition: A topographical perspective. Nature Reviews Neuroscience, 22(8), 503-513. doi.org/10.1038/s41583-021-00474-4

Sorella, S., Crescentini, C., Matiz, A., Chang, M., & Grecucci, A. (2025). resting-state BOLD temporal variability of the default mode network predicts spontaneous mind wandering, which is negatively associated with mindfulness skills. Frontiers in Human Neuroscience, 19, 1515902. https://doi.org/10.3389/fnhum.2025.1515902

Souter, N. E., de Freitas, A., Zhang, M., Shao, X., del Jesus Gonzalez Alam, T. R., Engen, H., ... & Jefferies, E. (2024). Default mode network shows distinct emotional and contextual responses yet common effects of retrieval demands across tasks. Human Brain Mapping, 45(7), e26703. https://doi.org/10.1002/hbm.26703

Stern, E. R., Eng, G. K., De Nadai, A. S., Iosifescu, D. V., Tobe, R. H., & Collins, K. A. (2022). Imbalance between default mode and sensorimotor connectivity is associated with perseverative thinking in obsessive-compulsive disorder. Translational Psychiatry, 12(1), 1-12. doi.org/10.1038/s41398-022-01780-w

Stöffel, T., Vaqué-Alcázar, L., Bartrés-Faz, D., Peró-Cebollero, M., Cañete-Massé, C., & Guàrdia-Olmos, J. (2024). Reduced default mode network effective connectivity in healthy aging is modulated by years of education. NeuroImage, 288, 120532. https://doi.org/10.1016/j.neuroimage.2024.120532

Sun, Y., Wang, S., Gan, S., Niu, X., Yin, B., Bai, G., Yang, X., Jia, X., Bai, L., & Zhang, M. (2021). Serum neuron-specific enolase levels associated with connectivity alterations in anterior default mode network after mild traumatic brain injury. Journal of Neurotrauma, 38(11), 1495-1505. doi.org/10.1089/neu.2020.7372

Terpou, B. A., Lloyd, C. S., Densmore, M., McKinnon, M. C., Théberge, J., Neufeld, R. W., ... & Lanius, R. A. (2022). Moral wounds run deep: exaggerated midbrain functional network connectivity across the default mode network in posttraumatic stress disorder. Journal of Psychiatry and Neuroscience, 47(1), E56-E66. doi: doi.org/10.1503/jpn.210117

Tripathi, V., Batta, I., Zamani, A., Atad, D. A., Sheth, S. K., Zhang, J., ... & Bauer, C. C. (2025). Default mode network functional connectivity as a transdiagnostic biomarker of cognitive function. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. https://doi.org/10.1016/j.bpsc.2024.12.016

Valencia, N., Seeger, F. R., Seitz, K. I., Carius, L., Nkrumah, R. O., Schmitz, M., ... & Herpertz, S. C. (2024). Childhood maltreatment and transdiagnostic connectivity of the default-mode network: the importance of duration of exposure. Journal of Psychiatric Research, 177, 239-248. https://doi.org/10.1016/j.jpsychires.2024.07.022

Vallat, R., Türker, B., Nicolas, A., & Ruby, P. (2022). High dream recall frequency is associated with increased creativity and default mode network connectivity. Nature and Science of Sleep, 14, 265.  doi: 10.2147/NSS.S342137

Vaughn, K. A., DeMaster, D., Kook, J. H., Vannucci, M., & Ewing‐Cobbs, L. (2022). Effective connectivity in the default mode network after paediatric traumatic brain injury. European Journal of Neuroscience, 55(1), 318-336. doi.org/10.1111/ejn.15546

Wahlheim, C. N., Christensen, A. P., Reagh, Z. M., & Cassidy, B. S. (2022). Intrinsic functional connectivity in the default mode network predicts mnemonic discrimination: A connectome‐based modeling approach. Hippocampus, 32(1), 21-37. doi.org/10.1002/hipo.23393

Wang, Y., Dai, C., Shao, Y., Wang, C., & Zhou, Q. (2022). Changes in ventromedial prefrontal cortex functional connectivity are correlated with increased risk-taking after total sleep deprivation. Behavioural Brain Research, 418, Article 113674. doi.org/10.1016/j.bbr.2021.113674

Webb, C. A., Israel, E. S., Belleau, E., Appleman, L., Forbes, E. E., & Pizzagalli, D. A. (2021). Mind-wandering in adolescents predicts worse affect and is linked to aberrant default mode network–salience network connectivity. Journal of the American Academy of Child & Adolescent Psychiatry, 60(3), 377-387. doi.org/10.1016/j.jaac.2020.03.010

Xu, H. Z., Peng, X. R., Liu, Y. R., Lei, X., & Yu, J. (2022). Sleep quality modulates the association between dynamic functional network connectivity and cognitive function in healthy older adults. Neuroscience, 480, 131-142. doi.org/10.1016/j.neuroscience.2021.11.018

Yeshurun, Y., Nguyen, M., & Hasson, U. (2021). The default mode network: Where the idiosyncratic self meets the shared social world. Nature Reviews Neuroscience, 22(3), 181-192. doi.org/10.1038/s41583-020-00420-w

Zhang, L., Qin, K., Pan, N., Xu, H., & Gong, Q. (2025). Shared and distinct patterns of default mode network dysfunction in major depressive disorder and bipolar disorder: A comparative meta-analysis. Journal of Affective Disorders, 368, 23-32. https://doi.org/10.1016/j.jad.2024.09.021

Zhang, J., Raya, J., Morfini, F., Urban, Z., Pagliaccio, D., Yendiki, A., ... & Whitfield-Gabrieli, S. (2023). Reducing default mode network connectivity with mindfulness-based fMRI neurofeedback: a pilot study among adolescents with affective disorder history. Molecular psychiatry, 28(6), 2540-2548. https://doi.org/10.1038/s41380-023-02032-z

Zhao, Y., Kirschenhofer, T., Harvey, M., & Rainer, G. (2024). Mediodorsal thalamus and ventral pallidum contribute to subcortical regulation of the default mode network. Communications Biology, 7(1), 891.  https://doi.org/10.1038/s42003-024-06531-9

Zhou, A. X., Duncan, J., & Mitchell, D. J. (2025). Specialized response of default mode subnetworks and multiple-demand regions to transitions of person, place and time. bioRxiv, 2025-01. https://doi.org/10.1101/2025.01.14.631412

Zuberer, A., Kucyi, A., Yamashita, A., Wu, C. M., Walter, M., Valera, E. M., & Esterman, M. (2021). Integration and segregation across large-scale intrinsic brain networks as a marker of sustained attention and task-unrelated thought. NeuroImage, 229, Article 117610. doi.org/10.1016/j.neuroimage.2020.117610

Zundel, C. G., Ely, S., Brokamp, C., Strawn, J. R., Jovanovic, T., Ryan, P., & Marusak, H. A. (2024). Particulate matter exposure and default mode network equilibrium during early adolescence. Brain Connectivity, 14(6), 307-318. https://doi.org/10.1089/brain.2023.0072

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Date of last update: 15-Jan-2023 TNT

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